This study involved four major activities in estimating the current size of the CAR T-cell therapy market. Exhaustive secondary research was carried out to collect information on the market, its peer markets, and its parent market. These findings, assumptions, and sizing were then validated with industry experts across the value chain through primary research. Both top-down and bottom-up approaches were employed to estimate the complete market size. Following this, market breakdown and data triangulation procedures were used to estimate the market size of segments and subsegments.
Secondary Research
Secondary research was used mainly to identify and collect information for the extensive, technical, market-oriented, and commercial study. The secondary sources referred for this research study include publications from government sources, such as the National Center for Biotechnology Information (NCBI), National Institutes of Health (NIH), World Health Organization (WHO), United States Food and Drug Administration (US FDA), American Society of Gene & Cell Therapy (ASGCT), European Medicines Agency (EMA), Industry Association of Synthetic Biology (IASB), International Society for Cell & Gene Therapy (ISCT), National Center for Complementary and Integrative Health (NCCIH), BioPharm International, ScienceDirect, News Articles, Journals, Press Releases, Paid Databases, Expert Interviews, and MarketsandMarkets Analysis, among others. Secondary sources also included corporate and regulatory filings (such as annual reports, SEC filings, investor presentations, and financial statements); business magazines and research journals; press releases; and trade, business, and professional associations. These sources were also used to obtain key information about major players, global product revenues, market classification, and segmentation according to industry trends, regional/country-level markets, market developments, and technology perspectives. Secondary data was collected and analyzed to arrive at the overall size of the global CAR T-cell therapy market, which was validated through primary research.
Primary Research
In-depth interviews were conducted with various primary respondents, including key industry participants, subject-matter experts (SMEs), C-level executives of key market players, and industry consultants, among other experts, to obtain and verify the critical qualitative and quantitative information as well as assess future prospects of the market. Various primary sources from both the supply and demand sides of the market were interviewed to obtain qualitative and quantitative information. The following is a breakdown of the primary respondents:

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Market Size Estimation
The global size of the CAR T-cell therapy market was estimated through multiple approaches. A detailed market estimation approach was followed to estimate and validate the value of the market and other dependent submarkets. These methods were also used extensively to estimate the size of various subsegments in the market. The research methodology used to estimate the market size includes the following:
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The major players in the industry and market have been identified through extensive primary and secondary research.
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The CAR T-cell therapy-related business shares of leading players have been determined through secondary research and primary analysis.
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All percentage shares, splits, and breakdowns have been determined using secondary sources and verified through primary sources.
Market Size Estimation Methodology-Bottom-up approach

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Top-down Approach-

Data Triangulation
After estimating the overall market size from the market size estimation process, the total market was split into several segments. To complete the overall market engineering process and arrive at the exact statistics for all segments, data triangulation and market breakdown procedures were employed, wherever applicable. The data was triangulated by studying various factors and trends from both the demand and supply sides.
Market Definition
CAR T-cell therapy is a treatment method wherein a patient's T-cells (a type of immune system cell) undergo modification in a laboratory to target and attack cancer cells effectively. Initially, T-cells are extracted from the patient's bloodstream. Then the gene for a special receptor that binds to a specific protein on the patient's cancer cells is added to the T cells in the laboratory. The special receptor is known as chimeric antigen receptor (CAR). Following this modification process, the CAR T-cells are cultured and multiplied in large quantities. Finally, the amplified CAR T-cells are administered to the patient via infusion. This therapeutic approach is predominantly utilized in the management of specific blood cancers, and ongoing research is exploring its potential applications in treating other forms of cancer. The CAR T-Cell therapy market includes approved and pipeline CAR T-cell products for therapy purpose.
Key Stakeholders
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Pharmaceutical Companies
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Biotechnology Companies
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Clinical Research Organizations (CROs)
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Regulatory Authorities
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Healthcare Providers
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Patients and Patient Advocacy Groups
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Investors and Venture Capital Firms
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Research & Development Companies
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Research Laboratories & Academic Institutes.
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Market Research & Consulting Firms
The main objectives of this study are as follows:
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To define, describe, and forecast the CAR T-cell therapy market by value for product, target, indication, demographic, end user, and region
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To define, describe, and forecast the CAR T-cell therapy market by volume for the product segment at global level.
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To provide detailed information regarding the major factors influencing the market growth (such as drivers, restraints, opportunities, and challenges)
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To analyze the micromarkets with respect to individual growth trends, prospects, and contributions to the overall CAR T-cell therapy market
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To analyze the opportunities for stakeholders and provide details of the competitive landscape for market leaders
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To forecast the size of the market segments with respect to five regions: North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa
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To profile the key players and analyze their market shares and core competencies
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To track and analyze competitive developments, such as product launches, partnerships, agreements, collaborations, and expansions.
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To benchmark players within the market using the proprietary “Company Evaluation Matrix” framework, which analyzes market players on various parameters within the broad categories of business and product excellence strategy.
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To provide an overview of the market with specialized analysis such as trends/distruptions impacting customers business, pricing analysis, value/ supply chain analysis, ecosystem analysis, technology analysis, patent analysis, key conferences & events 2024-2025, regulatory landscape, porter’s five forces’ analysis, key stakeholder and buying criteria, and investment and funding scenario
Available Customizations
With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for this report with additional efforts:
Product Information
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Country-wise Information: Analysis for additional countries (up to five)
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Company Information: Detailed analysis and profiling of additional key market players across the globe
Growth opportunities and latent adjacency in CAR T-cell Therapy Market